Gynecology24 August 20262 min read

Endometriosis and Infertility: Surgery or IVF?

In short: Many women with endometriosis conceive naturally, but endometriosis is common among women with infertility. Treatment depends on age, ovarian reserve, disease stage, pain and tubal status. Because surgery for endometriomas can reduce ovarian reserve, the order of surgery and IVF is planned carefully for women wanting pregnancy.

How does endometriosis affect fertility?

  • It creates an inflammatory environment that can impair egg, sperm and embryo function.
  • Adhesions can distort the tubes and their movement.
  • Endometriomas and surgery for them can reduce ovarian reserve.
  • Painful sex can make regular intercourse difficult.

Factors guiding treatment

  • Age and ovarian reserve (AMH, antral follicle count)
  • Severity of pain
  • Presence and size of endometriomas
  • Tubal patency
  • Partner's semen analysis
  • Duration of trying

When is surgery preferred?

For younger women with significant pain and good reserve, laparoscopic surgery can reduce pain and improve natural fertility; treating mild to moderate endometriosis laparoscopically has been shown to increase natural pregnancy rates. Surgery should preserve ovarian tissue as far as possible.

When is IVF preferred?

With older age, low reserve, tubal damage, male factor or no pregnancy after previous surgery, IVF is usually more appropriate. Routine removal of endometriomas before IVF is not recommended because it does not improve pregnancy rates and may reduce reserve; large cysts blocking egg collection or suspicious appearance are assessed separately.

If pregnancy must be delayed

Young women with endometriosis who must delay pregnancy, especially before ovarian surgery, should discuss egg freezing.

An individual approach

There is no single right path. Having gynaecological surgery and IVF assessed together by the same physician makes it easier to choose the right order.

Frequently Asked Questions

Does everyone with endometriosis become infertile?
No. Many women with endometriosis conceive naturally.
Should an endometrioma be removed before IVF?
Not routinely. The decision depends on cyst size, symptoms and ovarian reserve.

Sources

  1. ESHRE Guideline: Endometriosis, 2022.
  2. Practice Committee of the ASRM. Endometriosis and infertility: a committee opinion. Fertil Steril, 2012.

The information on this website is for general information only and does not replace a medical consultation.

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